Karunarathne K, Kee TR, Jeon H, Cazzaro S, Gamage YI, Pan J, Woo JA, Kang DE, Muschol M. Crystal Violet Selectively Detects Aβ Oligomers but Not Fibrils In Vitro and in Alzheimer's Disease Brain Tissue. Biomolecules. https://doi.org/10.3390/biom14060615 https://pubmed.ncbi.nlm.nih.gov/38927020//
Liu, T., Wetzel, L., Zhu, Z., Kumaraguru, P., Gorthi, V., Yan, Y., Bukhari, M. Z., Ermekbaeva, A., Jeon, H., Kee, T. R., Woo, J. A., Kang, D. E. Disruption of Mitophagy Flux through the PARL-PINK1 Pathway by CHCHD10 Mutations or CHCHD10 Depletion. Cells. https://doi.org/10.3390/cells12242781 https://pubmed.ncbi.nlm.nih.gov/38132101/
Alici, H., Uversky, V. N., Kang, D. E., Woo, J. A., Coskuner-Weber, O. The impacts of the mitochondrial myopathy-associated G58R mutation on the dynamic structural properties of CHCHD10. J Biomol Struct Dyn. https://doi.org/10.1080/07391102.2023.2227713 https://pubmed.ncbi.nlm.nih.gov/37349880/
Cazzaro, S., Zhao, X., Zhao, V. K., Kim, Y. K., Woo, J. A. Slingshot homolog-1 amplifies mitochondrial abnormalities by distinctly impairing health and clearance of mitochondria. Hum Mol Genet. https://doi: 10.1093/hmg/ddad006 https://pubmed.ncbi.nlm.nih.gov/36637427/
Alici, H., Uversky, V. N., Kang, D. E., Woo, J. A., Coskuner-Weber, O. Structures of the Wild-Type and S59L Mutant CHCHD10 Proteins Important in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia. ACS Chem Neurosci. https://doi: 10.1021/acschemneuro.2c00011 https://pubmed.ncbi.nlm.nih.gov/35349255/
Cazzaro, S., Woo, J. A., Wang, X., Liu, T., Rego, S., Kee, T. R., Koh, Y., Vázquez-Rosa, E., Pieper, A. A., Kang, D. E. Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease. Proc Natl Acad Sci USA https://doi.org/10.1073/pnas.2217128120 https://pubmed.ncbi.nlm.nih.gov/37463212/
Alici, H., Uversky, V. N., Kang, D. E., Woo, J. A., Coskuner-Weber, O. Effects of the Jokela type of spinal muscular atrophy-related G66V mutation on the structural ensemble characteristics of CHCHD10. Proteins https://doi.org/10.1002/prot.26463 https://pubmed.ncbi.nlm.nih.gov/36625206/
Woo, J. A., Castaño M., Kee, T. R., Lee, J., Koziol-White, C. J., An, S. S., Kim, D., Kang, D. E., Liggett, S. B. A Par3/LIM Kinase/Cofilin Pathway Mediates Human Airway Smooth Muscle Relaxation by TAS2R14. Am J Respir Cell Mol Biol https://doi.org/10.1165/rcmb.2022-0303OC https://pubmed.ncbi.nlm.nih.gov/36662576/
Alici, H., Uversky, V. N., Liu, T., Kang, D. E., Woo, J. A., Coskuner-Weber, O. Frontotemporal Dementia-Related V57E Mutation Impairs Mitochondrial Function and Alters the Structural Properties of CHCHD10. ACS Chem Neurosci https://doi.org/10.1021/acschemneuro.3c00125 https://pubmed.ncbi.nlm.nih.gov/37194187/
Yan, Y., Wang, X., Chaput, D., Shin, M. K., Koh, Y., Gan, L., Pieper, A. A., Woo, J. A., & Kang, D. E. X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women. Cell https://doi.org/10.1016/j.cell.2022.09.002 https://pubmed.ncbi.nlm.nih.gov/36198316/
Cazzaro, S., Fang, C., Khan, H., Witas, R., Kee, T. R., Woo, J. A., & Kang, D. E. Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics. Frontiers in aging neuroscience https://doi.org/10.3389/fnagi.2022.933979 https://pubmed.ncbi.nlm.nih.gov/36092812/
Kee, T., Wehinger, J., Gonzalez, P., Nguyen E., McGill Percy, KC., Khan S., Chaput D., Wang X., Liu T., Kang DE., Woo JA. Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation. Hum Mol Genet. DOI: 10.1093/hmg/ddac083 https://pubmed.ncbi.nlm.nih.gov/35786718/
Liu T., Woo JA., Bukhari, M., Wang X., Yan Y., Cazzaro S., Ermekbaeva, A., Sista, A., Kotsiviras, LePochat P., Chacko A., Zhao X., Kang DE. Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10. acta neuropathol commun https://doi.org/10.1186/s40478-022-01386-9 https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-022-01386-9
Woo JA., Yan Y., Kee, T., Cazzaro S., McGill Percy, KC., Wang X., Liu T., Liggett SB., Kang DE. β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy. Life Sci Alliance doi:10.26508/lsa.202101183 2021. https://pubmed.ncbi.nlm.nih.gov/34862271/
Kee, T., Gonzalez, P., Wehinger, J., Bukhari, M., Ermekbaeva, A., Sista, A., Kotsiviras, P., Liu, T., Kang, D.E., Woo, JA. Mitochondrial CHCHD2: Disease-Associated Mutations, Physicological Functions, and Current Animal Models Frontiers in Aging Neuroscience doi:10.3389/fnagi.2021.660843 2021. https://pubmed.ncbi.nlm.nih.gov/33967741/
Ren, D., Quan, N., He, Z., Fedorova, J., Zhang, J., Wood, E., Zhang, X., Kang, D.E., Li, J. Sestrin2 maintains OXPHOS integrity to modulate cardiac substrate metabolism during ischemia and reperfusion. Redox Biology http://doi.org/10.1016/j.redox.2020.101824. Online ahead of print. 2020. https://www.sciencedirect.com/science/article/pii/S2213231720310296?via%3Dihub
Palavicini, J.P., Chen, J., Wang, C., Wang, J., Qin, C. Bauerle, E., Woo, J.A., Kang, D.E., Musi, N., Dupree, J.L., Han, X. Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes. JCI Insight 5(21):137286. doi: 10.1172/jci.insight.137286 2020. https://insight.jci.org/articles/view/137286
Fang C, Woo JA, Liu T, Zhao X, Cazzaro S, Yan Y, Matlack J, Kee T, LePochat P, Kang DE. SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation Autophagy 2020 Oct. 12:1-22. doi:10.1080/15548627.2020.1816663. Online ahead of print. PMID: 33044112 2020. https://www.tandfonline.com/doi/full/10.1080/15548627.2020.1816663
Liu T, Woo JA, Bukhari MZ, LePochat P, Chacko A, Selenica MLB, Yan Y, Kotaiviras P, Buosi SC, Zhao X, Kang DE. CHCHD10-regulated OPA1-mitofilin complex mediates TDP-43-induced mitochondrial phenotypes associated with frontotemporal dementia FASEB journal: official publication of the Federation of American Societies for Experimental Biology 34(6):8493-8509, 2020. https://pubmed.ncbi.nlm.nih.gov/32369233/
Woo JA, Liu T, Fang CC, Castaño MA, Kee T, Yrigoin K, Yan Y, Cazzaro S, Matlack J, Wang X, Zhao X, Kang DE, Liggett SB. β-Arrestin2 oligomers impair the clearance of pathological tau and increase tau aggregates. Proceedings of the National Academy of Sciences of the United States of America. 117(9):5006-5015, 2020. https://www.ncbi.nlm.nih.gov/pubmed/32071246
Woo JA, Castaño M, Goss A, Kim D, Lewandowski EM, Chen Y, Liggett SB. Differential long-term regulation of TAS2R14 by structurally distinct agonists. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 33(11):12213-12225. doi: 10.1096/fj.201802627RR. 2019. https://pubmed.ncbi.nlm.nih.gov/31430434/
Kim D, Cho S, Castaño MA, Panettieri RA, Woo JA, Liggett SB Biased TAS2R Bronchodilators Inhibit Airway Smooth Muscle Growth by Downregulating Phosphorylated Extracellular Signal-regulated Kinase 1/2 American Journal of Respiratory Cell and Molecular Biology. 60(5):532-540. doi: 10.1165/rcmb.2018-0189OC. 2019. https://pubmed.ncbi.nlm.nih.gov/30365340/
Woo JA, Liu T, Fang CC, Cazzaro S, Kee T, LePochat P, Yrigoin K, Penn C, Zhao X, Wang X, Liggett SB, Kang DE. Activated cofilin excerbates tau pathology by impairing tau-mediated microtubule dynamics. Communications Biology. 22;2(1):112, 2019. https://www.ncbi.nlm.nih.gov/pubmed/30911686
Woo JA, Kang DE. Cofilin, a Master Node Regulating Cytoskeletal Pathogenesis in Alzheimer's Disease. Journal of Alzheimer's disease. 72(s1):S131-S144, 2019. https://www.ncbi.nlm.nih.gov/pubmed/31594228
Liu T, Woo JA, Yan Y, LePochat P, Bukhari MZ, Kang DE. Dual role of cofilin in APP trafficking and amyloid-β clearance. FASEB journal: official publication of the Federation of American Societies for Experimental Biology. 33(12):14234-14247, 2019. https://www.ncbi.nlm.nih.gov/pubmed/31646885
Kim D, Cho S, Woo JA, Liggett SB. A CREB-mediated increase in miRNA let-7f during prolonged β-agonist exposure: a novel mechanism of β 2-adrenergic receptor down-regulation in airway smooth muscle FASEB journal: official publication of the Federation of American Societies for Experimental Biology. 32(7):3680-3688. doi: 10.1096/fj.201701278R. Epub 2018. https://pubmed.ncbi.nlm.nih.gov/29455573/
Liu T, Wang F, LePochat P, Woo JA, Bukhari MZ, Hong KW, Trotter C, Kang DE. Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 Regulation. Scientific Reports. 7: 11532, 2017. https://www.ncbi.nlm.nih.gov/pubmed/28912445
Woo JA, Liu T, Zhao X, Trotter C, Yrigoin K, Cazzaro S, De Narvaez E, Khan H, Witas R, Bukhari A, Makati K, Wang X, Dickey C, Kang DE. Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone complexes. Hum Mol Genet. 26(20):3973-3988, 2017 https://www.ncbi.nlm.nih.gov/pubmed/29016855
Kim D, Woo JA, Geffken E, An SS, Liggett SB Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via G αi1,2,3 FASEB journal: official publication of the Federation of American Societies for Experimental Biology. 56(6):762-771. doi: 10.1165/rcmb.2016-0373OC. https://pubmed.ncbi.nlm.nih.gov/28145731/
Woo JA, Liu T, Trotter C, Fang C, De Narvaez E, LePochat P, Maslar D, Bukhari A, Zhao X, Deonarine D, Westerheide SD, Kang DE. Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity. Nat Commun. 8: 15558, 2017. https://www.ncbi.nlm.nih.gov/pubmed/28585542
Witas R, Chaput D, Khan H, Stevens SM Jr, Kang DE. Isolation and Proteomic Analysis of Microvesicles and Exosomes from HT22 Cells and Primary Neurons. Methods Mol Biol.. 1598: 255-67, 2017. https://www.ncbi.nlm.nih.gov/pubmed/28508366
Woo JA, Boggess T, Uhlar C, Wang X, Khan H, Cappos G, Joly-Amado A, De Narvaez E, Majid S, Minamide LS, Bamburg JR, Morgan D, Weeber E, Kang DE. RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction. Cell death & disease. 6: 1676, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25741591
Woo JA, Zhao X, Khan H, Penn C, Wang X, Joly-Amado A, Weeber E, Morgan D, Kang DE. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell death and differentiation. , 2015. http://www.ncbi.nlm.nih.gov/pubmed/25698445
Wang R, Palavicini JP, Wang H, Maiti P, Bianchi E, Xu S, Lloyd BN, Dawson-Scully K, Kang DE, Lakshmana MK. RanBP9 overexpression accelerates loss of dendritic spines in a mouse model of Alzheimer's disease. Neurobiology of disease. 69: 169-79, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24892886
Roh SE, Woo JA, Lakshmana MK, Uhlar C, Ankala V, Boggess T, Liu T, Hong YH, Mook-Jung I, Kim SJ, Kang DE. Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 27(12) : 4776-89, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23982146
Palavicini JP, Wang H, Bianchi E, Xu S, Rao JS, Kang DE, Lakshmana MK. RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer's brain synaptosomes. Cell death & disease. 4: e667, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23764848
Palavicini JP, Lloyd BN, Hayes CD, Bianchi E, Kang DE, Dawson-Scully K, Lakshmana MK. RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice. PloS one. 8(6) : e66908, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23840553
Song H, Boo JH, Kim KH, Kim C, Kim YE, Ahn JH, Jeon GS, Ryu H, Kang DE, Mook-Jung I. Critical role of presenilin-dependent γ-secretase activity in DNA damage-induced promyelocytic leukemia protein expression and apoptosis. Cell death and differentiation. 20(4) : 639-48, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23306558
Liu T, Roh SE, Woo JA, Ryu H, Kang DE. Cooperative role of RanBP9 and P73 in mitochondria-mediated apoptosis. Cell death & disease. 4: e476, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23348590
Jeon JP, Roh SE, Wie J, Kim J, Kim H, Lee KP, Yang D, Jeon JH, Cho NH, Kim IG, Kang DE, Kim HJ, So I. Activation of TRPC4β by Gαi subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron. Cell calcium. 54(4) : 307-19, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24011658
Almenar-Queralt A, Kim SN, Benner C, Herrera CM, Kang DE, Garcia-Bassets I, Goldstein LS. Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. The Journal of biological chemistry. 288(49) : 35222-36, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24145027
Woo JA, Roh SE, Lakshmana MK, Kang DE. Pivotal role of RanBP9 in integrin-dependent focal adhesion signaling and assembly. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(4) : 1672-81, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22223749
Lakshmana MK, Hayes CD, Bennett SP, Bianchi E, Reddy KM, Koo EH, Kang DE. Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(5) : 2072-83, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22294787
Woo JA, Jung AR, Lakshmana MK, Bedrossian A, Lim Y, Bu JH, Park SA, Koo EH, Mook-Jung I, Kang DE. Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration. Cell death and differentiation. 19(9) : 1413-23, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22361682
Shilling D, Mak DO, Kang DE, Foskett JK. Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels. The Journal of biological chemistry. 287(14) : 10933-44, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22311977
Kang DE, Roh SE, Woo JA, Liu T, Bu JH, Jung AR, Lim Y. The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders.Experimental neurobiology. 20(2) : 67-80, 2011. http://www.ncbi.nlm.nih.gov/pubmed/22110363
Cheung KH, Mei L, Mak DO, Hayashi I, Iwatsubo T, Kang DE, Foskett JK. Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons. Science signaling. 3(114) : ra22, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20332427
Lakshmana MK, Chung JY, Wickramarachchi S, Tak E, Bianchi E, Koo EH, Kang DE. A fragment of the scaffolding protein RanBP9 is increased in Alzheimer's disease brains and strongly potentiates amyloid-beta peptide generation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(1) : 119-27, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19729516
Lakshmana M, K, Roy S, S, Mi K, and Kang D, E. Amyloidogenic Processing of APP in lipid rafts.The Open Biology J. 3: 21-31, 2010. https://benthamopen.com/ABSTRACT/TOBIOJ-3-21
Boo JH, Song H, Kim JE, Kang DE, Mook-Jung I. Accumulation of phosphorylated beta-catenin enhances ROS-induced cell death in presenilin-deficient cells. PloS one. 4(1) : e4172, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19137062
Lakshmana MK, Yoon IS, Chen E, Bianchi E, Koo EH, Kang DE. Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation. The Journal of biological chemistry. 284(18) : 11863-72, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19251705
Lakshmana MK, Chen E, Yoon IS, Kang DE. C-terminal 37 residues of LRP promote the amyloidogenic processing of APP independent of FE65. Journal of cellular and molecular medicine. 12(6B) : 2665-74, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18373737
Yoon IS, Chen E, Busse T, Repetto E, Lakshmana MK, Koo EH, Kang DE. Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(11) : 2742-52, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17463224
Yoon IS, Pietrzik CU, Kang DE, Koo EH. Sequences from the low density lipoprotein receptor-related protein (LRP) cytoplasmic domain enhance amyloid beta protein production via the beta-secretase pathway without altering amyloid precursor protein/LRP nuclear signaling.The Journal of biological chemistry. 280(20) : 20140-7, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15772078
Chevallier NL, Soriano S, Kang DE, Masliah E, Hu G, Koo EH. Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation. The American journal of pathology. 167(1) : 151-9, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15972961
Kang DE, Yoon IS, Repetto E, Busse T, Yermian N, Ie L, Koo EH. Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling. The Journal of biological chemistry. 280(36) : 31537-47, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16014629
Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell. 110(6) : 751-62, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12297048
Soriano S, Kang DE, Fu M, Pestell R, Chevallier N, Zheng H, Koo EH. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing. The Journal of cell biology. 152(4) : 785-94, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11266469
Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature. 414(6860) : 212-6, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11700559
Van Uden E, Kang DE, Koo EH, Masliah E. LDL receptor-related protein (LRP) in Alzheimer's disease: towards a unified theory of pathogenesis. Microscopy research and technique. 50(4) : 268-72, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10936878
Kang DE, Pietrzik CU, Baum L, Chevallier N, Merriam DE, Kounnas MZ, Wagner SL, Troncoso JC, Kawas CH, Katzman R, Koo EH. Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway. The Journal of clinical investigation. 106(9) : 1159-66, 2000. http://www.ncbi.nlm.nih.gov/pubmed/11067868
Kang DE, Soriano S, Frosch MP, Collins T, Naruse S, Sisodia SS, Leibowitz G, Levine F, Koo EH. Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(11) : 4229-37, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10341227
Tanaka S, Chen X, Xia Y, Kang DE, Matoh N, Sundsmo M, Thomas RG, Katzman R, Thal LJ, Trojanowski JQ, Saitoh T, Ueda K, Masliah E. Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease. Neurology. 50(6) : 1556-62, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9633694
Zhang J, Kang DE, Xia W, Okochi M, Mori H, Selkoe DJ, Koo EH. Subcellular distribution and turnover of presenilins in transfected cells. The Journal of biological chemistry. 273(20) : 12436-42, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9575200
Katzman R, Kang D, Thomas R. Interaction of apolipoprotein E epsilon 4 with other genetic and non-genetic risk factors in late onset Alzheimer disease: problems facing the investigator.Neurochemical research. 23(3) : 369-76, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9482249
Komori N, Kittel A, Kang D, Shackelford D, Masliah E, Zivin JA, Saitoh T. Reversible ischemia increases levels of Alzheimer amyloid protein precursor without increasing levels of mRNA in the rabbit spinal cord. Brain research. Molecular brain research. 49(1-2) : 103-12, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9387869
Kang DE, Saitoh T, Chen X, Xia Y, Masliah E, Hansen LA, Thomas RG, Thal LJ, Katzman R. Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease. Neurology. 49(1) : 56-61, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9222170
Conrad C, Andreadis A, Trojanowski JQ, Dickson DW, Kang D, Chen X, Wiederholt W, Hansen L, Masliah E, Thal LJ, Katzman R, Xia Y, Saitoh T. Genetic evidence for the involvement of tau in progressive supranuclear palsy. Annals of neurology. 41(2) : 277-81, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9029080
Saitoh T, Kang D, Mallory M, DeTeresa R, Masliah E. Glial cells in Alzheimer's disease: preferential effect of APOE risk on scattered microglia. Gerontology. 43(1-2) : 109-18, 1997. http://www.ncbi.nlm.nih.gov/pubmed/8996833
Yoshimoto M, Iwai A, Kang D, Otero DA, Xia Y, Saitoh T. NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation. Proceedings of the National Academy of Sciences of the United States of America. 92(20) : 9141-5, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7568089
Dornan WA, Kang DE, McCampbell A, Kang EE. Bilateral injections of beta A(25-35) + IBO into the hippocampus disrupts acquisition of spatial learning in the rat. Neuroreport. 5(2) : 165-8, 1993. http://www.ncbi.nlm.nih.gov/pubmed/8111004